May 27, 2025, 1:02 pm | Read time: 9 minutes
Vaginal dryness is a significant concern for many women, leading them to use products to address the issue. One well-known option is Vagisan Moisturizing Cream. How effective is this product, and what alternatives are available?
Although about one in three women over 45 is affected, vaginal dryness is a topic women are reluctant to discuss. To alleviate symptoms like burning, itching, or pain during sex, many turn to Vagisan Moisturizing Cream. But does the popular cream deliver on its promises? A look at customer reviews on medpex.de provides insight and reveals that there are also convincing alternatives to Vagisan Moisturizing Cream.
What Causes Vaginal Dryness?
Hormonal Reasons
Vaginal dryness occurs when the natural lubrication of the vaginal mucosa is disrupted. This is usually due to a reduced production of estrogen, a hormone partly responsible for the moisture and elasticity of the mucous membranes. When estrogen levels drop, the mucosa becomes thinner, more sensitive, and produces less moisture. This often happens during the use of hormonal contraceptives, menopause, after childbirth, or during breastfeeding.
Psychological Stress
Emotional factors also play a role, as stress, lack of sleep, or challenging life phases can affect hormone balance.
Excessive Intimate Hygiene
Frequent washing with perfumed products can damage the natural protective layer of the mucosa. As a result, the sensitive vaginal skin dries out and becomes prone to irritation. Perfumed panty liners and intimate sprays, as well as tight, synthetic underwear, can also disrupt the protective vaginal flora and irritate the sensitive mucosa.
Important: In the intimate area, the principle “less is more” applies. Gentle, moderate care and mindful body awareness are often the best protection against unpleasant symptoms like vaginal dryness.
Lifestyle and Diet
Insufficient hydration, unhealthy diet, smoking, or lack of exercise directly affect the skin, including the intimate area. Consistently depriving the body of nutrients or impairing circulation through smoking risks weak, dry mucosa.
Medications and Illnesses
Medications like antidepressants or antihistamines, chronic illnesses, cancer therapy, or antibiotic use can affect hormone balance and negatively impact vaginal moisture.
How Long Does It Take for Vaginal Flora to Regenerate?
The regeneration of vaginal flora largely depends on the cause of the dryness. After an infection or medication-related stress, it can take a few days to a few weeks. If dryness is caused by hormonal changes, regeneration can take several weeks, especially if no supportive measures are taken. Products like Vagisan can effectively support the process.
When Is Vaginal Dryness a Problem?
A dry vaginal mucosa is generally very uncomfortable, as it can be accompanied by burning, itching, or pain during intercourse. In severe cases, it can even lead to minor injuries and recurring infections. Emotional well-being often suffers from these symptoms, especially when intimacy and sexuality are affected.
When Should You Use Products Like Vagisan Moisturizing Cream?
As soon as the first uncomfortable symptoms—like a feeling of tightness, burning, or dryness in the intimate area—appear, it is worth taking action. If gentle measures like mild care or avoiding aggressive intimate wash lotions are not enough, a moisturizing cream like Vagisan can provide quick and immediate relief. Those who regularly experience symptoms or pain during sex should not hesitate to try a suitable product and ideally seek medical advice beforehand.
When Does Vagisan Moisturizing Cream Help?
The hormone-free cream is used for symptoms of vaginal dryness, especially during menopause. It can be applied externally in the intimate area or internally with an applicator, ideally before bedtime. Many young women also use it as a gentle alternative to conventional water-based lubricants. A particular advantage: Unlike traditional lubricants, it does not need to be applied immediately before intercourse. Regular use protects and cares for the intimate area, as it not only provides moisture but also has the nourishing properties of a cream.
How Does Vagisan Moisturizing Cream Work?
Vagisan Moisturizing Cream combines nourishing lipids with lactic acid. This combination ensures that the vaginal mucosa is not only moisturized but also stabilized in its natural pH value. The cream feels pleasantly soft, absorbs well, and leaves no sticky residue.
What Is Special About Vagisan Moisturizing Cream?
Unlike many lubricants, Vagisan is based on a water-oil formula. This means it not only provides short-term moisture but also nourishes the skin sustainably. The absence of hormones makes it suitable for women who want or need to avoid hormonal products. Additionally, the practical applicator solution allows for targeted application inside the vagina.
Side Effects
The cream is well tolerated. Only in rare cases can it cause mild irritation or allergic reactions, which usually subside quickly. If in doubt or if there are existing skin conditions, it is always advisable to consult a doctor.
Can You Use Vagisan Moisturizing Cream Long-Term?
Vagisan Moisturizing Cream is suitable for long-term use if no intolerances occur. Since it is hormone-free and its ingredients are well tolerated, the cream can be used over an extended period, such as throughout menopause or for chronic vaginal dryness. Many women report using Vagisan regularly and without problems, about two to three times a week. As with all care products, you should always listen to your own body. If redness, burning, or irritation occurs, the application should be paused, and if necessary, a gynecologist should be consulted.
Customer Opinions on Vagisan Moisturizing Cream
The reviews of Vagisan Moisturizing Cream on medpex.de are overall very positive. With an average rating of 4.7 out of 5 stars, many customers praise the immediate relief of symptoms. The easy application, pleasant skin feel, and good tolerability are frequently highlighted. Some women report feeling a better body sensation and more desire during sex after just a few applications. Criticism is rare and is mostly due to individual intolerances or the desire for even more convenient packaging.
Alternatives to Vagisan Moisturizing Cream
Creams
KadeFungin Moisturizing Gel
Provides intensive moisture, hormone-free, with hyaluronic acid.
Thanks to the hyaluronic acid it contains, a natural moisturizer, the gel provides long-lasting moisture and supports the regeneration of the vaginal mucosa. It is hormone-free, odorless, and contains no colorants or fragrances, making it particularly suitable for sensitive skin.
Special Feature
The combination of hyaluronic acid and glycerol ensures intensive hydration without affecting the natural vaginal flora. The handy dosing dispenser allows for particularly hygienic and easy application.
Customer Opinions
Customers appreciate the effective relief of dryness symptoms, the good tolerability of the gel, the easy application, and the pleasant, non-sticky consistency.
Multi-Gyn ActiGel
Supports vaginal flora and acts antibacterial against odor and discharge.
Multi-Gyn ActiGel is a versatile gel that not only helps with vaginal dryness but also acts as an antibacterial and supports the vaginal flora. It is based on the patented 2QR complex, a natural ingredient from Aloe barbadensis, which neutralizes harmful bacteria without affecting beneficial lactic acid bacteria.
Special Features
The gel is hormone-free, contains no fragrances, and is vegan. It can be used to prevent and treat bacterial vaginosis, itching, burning, discharge, and unpleasant odor. Some customers report a brief burning sensation after application, which quickly subsides.
Customer Opinions
Many women praise the quick relief of their symptoms and the versatile use of the gel. It is often recommended for preventing infections and as supportive care after antibiotic treatments due to its good tolerability and effective action.
Tablets
Vagiflor Lactic Acid Bacteria
The vaginal suppositories contain the lactic acid bacteria strain Lactobacillus acidophilus, which helps restore and maintain a healthy vaginal flora. They support the stabilization of the healthy vaginal pH value (3.8–4.5) and promote the natural defense function of the vagina.
Special Features
The suppositories are particularly suitable for use in cases of vaginal flora disturbances after antibiotic treatments, recurring vaginal infections, and before and after gynecological procedures. They can also be used during pregnancy and breastfeeding.
Customer Opinions
Customers find them very well tolerated and emphasize the quick relief of their symptoms and a noticeable improvement in vaginal well-being.
Gynoflor Tablets
Contain lactic acid and estrogen, comprehensively regenerate the mucosa (prescription required).
Gynoflor combines lactic acid bacteria with the estrogen estriol. This combination helps restore the vaginal flora after infections or antibiotic treatments and alleviates symptoms like itching, burning, and pain during intercourse caused by estrogen deficiency, especially after menopause.
Special Features
The combination of lactic acid bacteria and estriol allows for comprehensive regeneration of the vaginal mucosa.
Customer Opinions
Customers report a significant improvement in symptoms and a noticeable regeneration of the vaginal mucosa.
Lubricants
Durex Play Feel Lubricant
The lubricant is ideal for use in cases of hormonally induced vaginal dryness. It can be applied before or during intercourse to increase lubrication and enhance intimate comfort. Thanks to its gentle formula, it is also suitable for daily use.
Special Features
Durex Play Feel Lubricant is water-based and pH-friendly, contains no artificial fragrances or colorants, does not stick, and is easy to wash off. Dermatologically and gynecologically tested, it impresses with high skin compatibility and is therefore also ideal for sensitive skin.
Customer Opinions
The consistency is perceived as very pleasant, and the immediate relief of dryness is highly appreciated. However, some users report that the gel needs to be reapplied with prolonged use as it absorbs quickly.
Ritex Bio
The lubricant can be applied before or during intercourse to increase lubrication and avoid uncomfortable friction. Thanks to its gentle formula, it is also suitable for daily use.
Special Features
The lubricant is made from high-quality, vegan raw materials and is completely free of fragrances, colorants, PEG, parabens, and other preservatives. Dermatological tests rated its skin compatibility as “Very Good,” making it ideal for sensitive skin.
Customer Opinions
Users particularly appreciate its compatibility with sensitive skin, its efficiency, and its pleasant scent. However, it is sometimes perceived as slightly sticky.
Better Avoid Home Remedies
Olive oil, coconut oil, or saliva are not suitable moisturizers or lubricants for the intimate area. These substances can disrupt the delicate balance of the vaginal flora and increase the risk of infections. Saliva, in particular, contains bacteria that have no place in the intimate area. Vaseline or baby oil can also leave residues and irritate the skin barrier. It’s better to rely on tested products specifically developed for vaginal care.

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Conclusion
Vagisan Moisturizing Cream is a convincing product that helps many women quickly and reliably. Those suffering from mild to moderate vaginal dryness will find a hormone-free and well-tolerated solution in the cream. However, it is worth trying alternatives as well. If your symptoms persist over a longer period or worsen, you should consult your gynecologist, especially in cases of recurring infections or pain.